Search on: NEXIN, PROTEASE-ASSOCIATED 
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Descriptor English:   Protease Nexins 
Descriptor Spanish:   Nexinas de Proteasas 
Descriptor Portuguese:   Nexinas de Proteases 
Synonyms English:   Nexin, Protease
Nexin, Protease-Associated
Nexin, Protease Associated
Nexins, Protease
Protease Nexin
Protease-Associated Nexin  
Tree Number:   D12.644.822.468
D12.776.645.468
Definition English:   Extracellular protease inhibitors that are secreted from FIBROBLASTS. They form a covalent complex with SERINE PROTEASES and can mediate their cellular internalization and degradation. 
History Note English:   2011 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   54058 
Unique Identifier:   D058255 

Occurrence in VHL:
 

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